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Symbol Name ID |
Dnase1
deoxyribonuclease I MGI:103157 |
| Darker colors indicate more annotations |
| Human Phenotypes | Leukopenia |
Pericarditis |
Lymphadenopathy |
Lupus nephritis |
Nephritis |
Abnormality of the immune system |
Discoid lupus rash |
Malar rash |
Serositis |
Decreased circulating complement C3 concentration |
Decreased circulating complement C4 concentration |
Anti-complement component C1q antibody positivity |
Anti-phosphatidic acid antibody positivity |
Anti-ribosome Po antibody positivity |
Anti-Ro52/TRIM21 antibody positivity |
Anti-titin antibody positivity |
Antineutrophil antibody positivity |
Perinuclear antineutrophil antibody positivity |
Antinuclear antibody positivity |
Anti-dsDNA antibody positivity |
Anti-nucleoporin 62 antibody positivity |
Anti-La/SS-B antibody positivity |
Anti-Sm antibody positivity |
Anti-U1 ribonucleoprotein antibody positivity |
Antiphospholipid antibody positivity |
Systemic lupus erythematosus |
| Disease(s) Associated with DNASE1 | ||||||||||||||||||||||||||
| systemic lupus erythematosus |
| Mouse Phenotypes | increased susceptibility to systemic lupus erythematosus |
increased autoantibody level |
increased anti-nuclear antigen antibody level |
increased anti-double stranded DNA antibody level |
increased anti-histone antibody level |
glomerulonephritis |
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| Availability | Mouse Genotype | ||||||
| Dnase1tm2092.1Arte/Dnase1tm2092.1Arte | |||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/03/2024 MGI 6.24 |
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