Symbol Name ID |
Cdkn1a
cyclin dependent kinase inhibitor 1A MGI:104556 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Mouse Phenotypes | immune system phenotype |
impaired macrophage chemotaxis |
increased T cell proliferation |
abnormal thymus physiology |
enlarged spleen |
increased spleen weight |
spleen hyperplasia |
increased B cell number |
increased memory T cell number |
decreased monocyte cell number |
abnormal CD4-positive, alpha beta T cell morphology |
abnormal spleen morphology |
increased IgG1 level |
enlarged lymph nodes |
lymph node hyperplasia |
enlarged cervical lymph nodes |
abnormal self tolerance |
decreased susceptibility to induced arthritis |
increased autoantibody level |
increased anti-nuclear antigen antibody level |
increased anti-double stranded DNA antibody level |
increased anti-histone antibody level |
increased anti-single stranded DNA antibody level |
glomerulonephritis |
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Availability | Mouse Genotype | ||||||||||||||||||||||||
Cdkn1atm1.1(KOMP)Vlcg/Cdkn1atm1.1(KOMP)Vlcg | |||||||||||||||||||||||||
Cdkn1atm1Led/Cdkn1atm1Led | |||||||||||||||||||||||||
Cdkn1atm1Tyj/Cdkn1atm1Tyj | * |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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