Symbol Name ID |
Ifngr2
interferon gamma receptor 2 MGI:107654 |
* | Aspects of the system are reported to show a normal phenotype. |
! | Indicates phenotype varies with strain background. |
Darker colors indicate more annotations |
Human Phenotypes | Immunodeficiency |
Recurrent mycobacterial infections |
Disease(s) Associated with IFNGR2 | ||
immunodeficiency 28 |
Mouse Phenotypes | immune system phenotype |
abnormal diapedesis |
insulitis |
ovary inflammation |
abnormal class switch recombination |
abnormal T-helper 1 cell differentiation |
abnormal splenic cell ratio |
abnormal T-helper 1 physiology |
abnormal T-helper 2 physiology |
abnormal cytotoxic T cell physiology |
decreased susceptibility to type IV hypersensitivity reaction |
decreased interferon-gamma secretion |
decreased interleukin-4 secretion |
decreased tumor necrosis factor secretion |
decreased susceptibility to autoimmune diabetes |
myositis |
increased susceptibility to bacterial infection |
increased susceptibility to parasitic infection |
|
Availability | Mouse Genotype | ||||||||||||||||||
Ifngr2tm1Pbro/Ifngr2tm1Pbro | |||||||||||||||||||
Tg(CD2-Ifngr2)1Pbro/? | * | ||||||||||||||||||
Tg(CD2-Ifngr2)2Pbro/? | * | ! | ! | ! |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/21/2024 MGI 6.24 |
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