Symbol Name ID |
Traf3
TNF receptor-associated factor 3 MGI:108041 |
Darker colors indicate more annotations |
Mouse Phenotypes | decreased B cell apoptosis |
decreased thymocyte number |
enlarged spleen |
abnormal B cell differentiation |
increased transitional stage B cell number |
decreased double-positive T cell number |
decreased mature B cell number |
increased follicular B cell number |
increased marginal zone B cell number |
increased B cell number |
decreased CD4-positive, alpha-beta T cell number |
decreased CD8-positive, alpha-beta T cell number |
decreased T cell number |
decreased leukocyte cell number |
abnormal leukocyte morphology |
spleen hypoplasia |
abnormal spleen germinal center morphology |
increased spleen white pulp amount |
abnormal B cell physiology |
increased IgA level |
increased IgG2a level |
increased IgG2b level |
increased IgG3 level |
decreased IgG level |
increased IgG level |
increased IgM level |
abnormal T cell physiology |
abnormal immune system organ morphology |
abnormal lymph node B cell domain morphology |
enlarged lymph nodes |
lymph node hyperplasia |
abnormal immune system physiology |
abnormal adaptive immunity |
impaired humoral immune response |
autoimmune response |
increased anti-double stranded DNA antibody level |
decreased response to antigen |
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Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||||
Traf3m1Btlr/Traf3m1Btlr | ||||||||||||||||||||||||||||||||||||||
Traf3m2Btlr/Traf3m2Btlr | ||||||||||||||||||||||||||||||||||||||
Traf3tm1Bal/Traf3tm1Bal | ||||||||||||||||||||||||||||||||||||||
Traf3tm1Bshp/Traf3tm1Bshp Cd19tm1(cre)Cgn/Cd19+ (conditional) |
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Cd19tm1(cre)Cgn/Cd19+ Traf3tm1Rbr/Traf3tm1Rbr (conditional) |
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Tg(Lck-cre)I57Jxm/? Traf3tm1Rbr/Traf3tm1Rbr (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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