Symbol
Name
ID

Crebbp
CREB binding protein
MGI:1098280

Phenotype annotations related to immune system

Darker colors indicate more annotations

Mouse Phenotypes

small thymus

decreased thymocyte number

enlarged spleen

decreased double-positive T cell number

increased double-positive T cell number

abnormal granulocyte morphology

increased granulocyte number

decreased B cell number

absent pre-B cells

decreased CD4-positive, alpha-beta T cell number

increased CD8-positive, alpha-beta T cell number

decreased T cell number

decreased lymphocyte cell number

abnormal leukocyte morphology

abnormal tumor necrosis factor level

Availability

Mouse Genotype

Crebbp^tm1Pkb/Crebbp^tm1Pkb

Crebbp^{Gt(U-San)112Imeg}/Crebbp⁺

Crebbp^tm1Dli/Crebbp⁺

Crebbp^tm1Jvd/Crebbp^tm1Jvd
Tg(MMTV-cre)4Mam/0 (conditional)

Crebbp^tm1Jvd/Crebbp^tm1Jvd
Tg(Lck-cre)548Jxm/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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