Symbol
Name
ID

Ncr1
natural cytotoxicity triggering receptor 1
MGI:1336212

Phenotype annotations related to immune system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Mouse Phenotypes

immune system phenotype

decreased NK cell number

increased NK cell number

decreased CD4-positive, alpha-beta T cell number

decreased CD8-positive, alpha-beta memory T cell number

decreased CD8-positive, alpha-beta T cell number

abnormal NK cell physiology

impaired natural killer cell mediated cytotoxicity

increased susceptibility to bacterial infection

decreased susceptibility to Herpesvirales infection induced morbidity/mortality

decreased susceptibility to Orthomyxoviridae infection induced morbidity/mortality

increased susceptibility to Orthomyxoviridae infection induced morbidity/mortality

decreased susceptibility to Herpesvirales infection

Availability

Mouse Genotype

Ncr1^noe/Ncr1^noe

Ncr1^{tm1.1(icre)Viv}/Ncr1^{tm1.1(icre)Viv}

Ncr1^tm1Oman/Ncr1^tm1Oman

Ncr1^tm2.1Viv/Ncr1⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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