Symbol
Name
ID

Gmds
GDP-mannose 4, 6-dehydratase
MGI:1891112

Phenotype annotations related to immune system

Darker colors indicate more annotations

Mouse Phenotypes

decreased transitional stage T2 B cell number

increased neutrophil cell number

increased granulocyte number

decreased plasmacytoid dendritic cell number

decreased dendritic cell number

decreased KLRG1-positive NK cell number

increased immature NK cell number

decreased Ly6C-positive mature NK cell number

decreased mature NK cell number

increased memory-marker NK cell number

decreased NK cell number

decreased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number

increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number

decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number

decreased CD4-positive, alpha-beta T cell number

increased CD4-positive, alpha-beta T cell number

decreased effector memory CD8-positive, alpha-beta T cell number

decreased CD8-positive, naive alpha-beta T cell number

decreased KLRG1+ CD8 alpha-beta T cell number

decreased CD8-positive, alpha-beta T cell number

increased CD8-positive, alpha-beta T cell number

decreased memory-marker CD4-negative NK T cell number

increased CD4-negative NK T cell number

decreased memory-marker CD4-positive NK T cell number

decreased CD4-positive NK T cell number

increased Ly6C-positive NK T cell number

increased NK T cell number

decreased alpha-beta T cell number

decreased T-helper cell number

increased gamma-delta T cell number

decreased regulatory T cell number

decreased macrophage cell number

increased monocyte cell number

increased leukocyte cell number

Availability

Mouse Genotype

Gmds^{tm1a(KOMP)Wtsi}/Gmds^{tm1a(KOMP)Wtsi}

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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