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Symbol
Name
ID

Peli1
pellino 1
MGI:1914495

Phenotype annotations related to immune system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Mouse Phenotypes

immune system phenotype

increased B cell apoptosis

decreased B cell proliferation

enlarged spleen

increased spleen weight

increased neutrophil cell number

abnormal spleen morphology

decreased circulating interferon-beta level

decreased circulating interleukin-12b level

decreased circulating interleukin-6 level

decreased circulating tumor necrosis factor level

enlarged lymph nodes

abnormal peripheral lymph node morphology

lymphoid hyperplasia

abnormal cytokine secretion

decreased interferon-alpha secretion

decreased interferon-beta secretion

decreased interleukin-10 secretion

decreased interleukin-12 secretion

decreased interleukin-6 secretion

decreased tumor necrosis factor secretion

decreased susceptibility to endotoxin shock

Availability

Mouse Genotype

Peli1^tm1.1Arte/Peli1^tm1.1Arte

*

Peli1^{tm1b(EUCOMM)Wtsi}/Peli1^{tm1b(EUCOMM)Wtsi}

Peli1^tm1Tigm/Peli1^tm1Tigm

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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