Symbol
Name
ID

Slc29a3
solute carrier family 29 (nucleoside transporters), member 3
MGI:1918529

Phenotype annotations related to immune system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Histiocytosis	Lymphadenopathy	Cervical lymphadenopathy	Splenomegaly	Hepatosplenomegaly	Episcleritis
Disease(s) Associated with SLC29A3
histiocytosis-lymphadenopathy plus syndrome

Mouse Phenotypes

immune system phenotype

increased macrophage apoptosis

abnormal thymus morphology

small thymus

enlarged spleen

increased spleen weight

myeloid hyperplasia

increased macrophage cell number

increased leukocyte cell number

abnormal macrophage morphology

abnormal spleen morphology

abnormal macrophage physiology

abnormal lymph node morphology

enlarged lymph nodes

increased susceptibility to bacterial infection

increased susceptibility to bacterial infection induced morbidity/mortality

Availability

Mouse Genotype

Slc29a3^em1(IMPC)Mbp/Slc29a3^em1(IMPC)Mbp

Slc29a3^{em1(IMPC)Wtsi}/Slc29a3^{em1(IMPC)Wtsi}

Slc29a3^tm1Lex/Slc29a3^tm1Lex

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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