Symbol Name ID |
Tnip1
TNFAIP3 interacting protein 1 MGI:1926194 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Mouse Phenotypes | immune system phenotype |
increased B cell proliferation |
increased susceptibility to induced colitis |
enlarged spleen |
increased spleen weight |
spleen hyperplasia |
increased basophil cell number |
increased neutrophil cell number |
increased granulocyte number |
increased plasmacytoid dendritic cell number |
increased dendritic cell number |
increased germinal center B cell number |
decreased B-2 B cell number |
increased B-1a cell number |
increased B-1b cell number |
increased plasma cell number |
decreased B cell number |
increased B cell number |
increased T follicular helper cell number |
increased memory T cell number |
decreased lymphocyte cell number |
increased large unstained cell number |
increased macrophage cell number |
increased monocyte cell number |
abnormal leukocyte morphology |
abnormal plasma cell morphology |
abnormal effector T cell morphology |
increased spleen red pulp amount |
abnormal spleen germinal center morphology |
increased spleen white pulp amount |
increased IgA level |
increased IgE level |
increased IgG1 level |
increased IgG2a level |
increased IgG2b level |
increased IgG3 level |
increased IgG level |
increased IgM level |
increased immunoglobulin level |
abnormal immune system morphology |
abnormal Peyer's patch morphology |
enlarged lymph nodes |
lymph node hyperplasia |
abnormal complement pathway |
decreased interleukin-12 secretion |
increased interleukin-12 secretion |
decreased interleukin-12b secretion |
increased interleukin-12b secretion |
increased interleukin-23 secretion |
increased interleukin-6 secretion |
increased tumor necrosis factor secretion |
increased susceptibility to systemic lupus erythematosus |
increased anti-nuclear antigen antibody level |
increased anti-double stranded DNA antibody level |
glomerulonephritis |
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Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
Tnip1Gt(E059E05)Wrst/Tnip1Gt(E059E05)Wrst | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Tnip1m1Btlr/Tnip1m1Btlr | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Tnip1tm1.1Pcoh/Tnip1tm1.1Pcoh | * | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
Tnip1tm1.2Pcoh/Tnip1tm1.2Pcoh | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Tnip1tm1b(EUCOMM)Hmgu/Tnip1tm1b(EUCOMM)Hmgu | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Tnip1tm1.1Pcoh/Tnip1+ | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Tnip1tm1.2Ama/Tnip1tm1.2Ama Tg(Itgax-cre)1-1Reiz/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/03/2024 MGI 6.24 |
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