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Symbol Name ID |
N4bp1
NEDD4 binding protein 1 MGI:2136825 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | immune system phenotype |
increased germinal center B cell number |
increased activated T cell number |
increased Ly6C high monocyte number |
abnormal macrophage physiology |
increased circulating interleukin-6 level |
increased circulating tumor necrosis factor level |
decreased interleukin-6 secretion |
increased interleukin-6 secretion |
increased tumor necrosis factor secretion |
lung inflammation |
decreased susceptibility to bacterial infection induced morbidity/mortality |
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| Availability | Mouse Genotype | ||||||||||||
| N4bp1em1Vmd/N4bp1em1Vmd | * | ||||||||||||
| N4bp1tm1.2Vmd/N4bp1tm1.2Vmd | |||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 07/02/2024 MGI 6.13 |
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