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Symbol
Name
ID

Nlrp12
NLR family, pyrin domain containing 12
MGI:2676630

Phenotype annotations related to immune system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Leukocytosis	Recurrent aphthous stomatitis	Lymphadenopathy	Splenomegaly	Erythema nodosum	Skin rash
Disease(s) Associated with NLRP12
familial cold autoinflammatory syndrome 2

Mouse Phenotypes		immune system phenotype	impaired neutrophil chemotaxis	abnormal leukocyte migration	increased susceptibility to induced colitis	enlarged spleen	decreased neutrophil cell number	abnormal cytokine level	abnormal chemokine level	decreased susceptibility to type IV hypersensitivity reaction	increased inflammatory response
Availability	Mouse Genotype	immune system phenotype	impaired neutrophil chemotaxis	abnormal leukocyte migration	increased susceptibility to induced colitis	enlarged spleen	decreased neutrophil cell number	abnormal cytokine level	abnormal chemokine level		increased inflammatory response
	Nlrp12^tm1Jpyt/Nlrp12^tm1Jpyt	*
	Nlrp12^tm1Tdk/Nlrp12^tm1Tdk

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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