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Symbol Name ID |
Zfat
zinc finger and AT hook domain containing MGI:2681865 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | immune system phenotype |
increased T cell apoptosis |
decreased T cell proliferation |
abnormal thymus morphology |
enlarged thymus |
enlarged spleen |
abnormal CD8-positive, alpha-beta T cell differentiation |
decreased CD4-positive, alpha-beta T cell number |
decreased CD8-positive, alpha-beta T cell number |
abnormal spleen morphology |
abnormal CD4-positive, alpha-beta T cell physiology |
decreased interleukin-2 secretion |
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| Availability | Mouse Genotype | ||||||||||||
| Zfatem1(IMPC)Ccpcz/Zfat+ | |||||||||||||
| Zfattm2.1Sawa/Zfattm2.1Sawa Tg(Cd4-cre)1Cwi/0 (conditional) |
* | ||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 07/02/2024 MGI 6.13 |
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