Symbol Name ID |
Nlrc4
NLR family, CARD domain containing 4 MGI:3036243 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Mouse Phenotypes | immune system phenotype |
enlarged spleen |
increased neutrophil cell number |
increased T cell number |
abnormal spleen morphology |
increased splenocyte number |
abnormal macrophage physiology |
increased circulating interleukin-1 beta level |
increased circulating interleukin-17 level |
abnormal cytokine secretion |
decreased interleukin-1 beta secretion |
increased interleukin-1 beta secretion |
decreased inflammatory response |
increased inflammatory response |
joint inflammation |
arthritis |
skin inflammation |
dermatitis |
abnormal response to infection |
increased susceptibility to bacterial infection |
increased susceptibility to bacterial infection induced morbidity/mortality |
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Availability | Mouse Genotype | |||||||||||||||||||||
Nlrc4em1Vnce/Nlrc4em1Vnce | ||||||||||||||||||||||
Nlrc4em2Vnce/Nlrc4em2Vnce | ||||||||||||||||||||||
Nlrc4em3Vnce/Nlrc4em3Vnce | * | |||||||||||||||||||||
Nlrc4m1Btlr/Nlrc4m1Btlr | ||||||||||||||||||||||
Nlrc4tm1Gln/Nlrc4tm1Gln | * | |||||||||||||||||||||
Nlrc4tm1Gne/Nlrc4tm1Gne | * | |||||||||||||||||||||
Nlrc4tm1Nnz/Nlrc4tm1Nnz | ||||||||||||||||||||||
Nlrc4tm1Vmd/Nlrc4tm1Vmd | ||||||||||||||||||||||
Nlrc4m1Btlr/Nlrc4+ | ||||||||||||||||||||||
Tg(Cd74-Nlrc4*)1Kyas/0 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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