Symbol Name ID |
Bcl2
B cell leukemia/lymphoma 2 MGI:88138 |
Darker colors indicate more annotations |
Human Phenotypes | Acute myeloid leukemia |
Disease(s) Associated with BCL2 | |
acute myeloid leukemia |
Mouse Phenotypes | increased B cell apoptosis |
increased T cell apoptosis |
increased macrophage apoptosis |
increased splenocyte apoptosis |
decreased B cell proliferation |
abnormal thymus morphology |
small thymus |
thymus atrophy |
decreased thymocyte number |
abnormal thymus involution |
enlarged spleen |
abnormal leukopoiesis |
abnormal B cell differentiation |
decreased immature B cell number |
increased immature B cell number |
abnormal T cell differentiation |
increased double-negative T cell number |
decreased double-positive T cell number |
decreased mature B cell number |
increased mature B cell number |
decreased B cell number |
decreased pre-B cell number |
increased B cell number |
increased pre-B cell number |
decreased CD8-positive, alpha-beta T cell number |
decreased T cell number |
decreased lymphocyte cell number |
abnormal lymphocyte morphology |
abnormal CD4-positive, alpha beta T cell morphology |
abnormal CD8-positive, alpha beta T cell morphology |
abnormal spleen morphology |
abnormal spleen red pulp morphology |
decreased spleen weight |
small spleen |
spleen atrophy |
abnormal spleen white pulp morphology |
decreased spleen white pulp amount |
abnormal lymphocyte physiology |
abnormal B cell physiology |
abnormal B cell activation |
abnormal T cell physiology |
abnormal immune system organ morphology |
enlarged lymph nodes |
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Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||||||||||
Bcl2tm1Dlo/Bcl2tm1Dlo | ||||||||||||||||||||||||||||||||||||||||||||
Bcl2tm1Lbox/Bcl2tm1Lbox | ||||||||||||||||||||||||||||||||||||||||||||
Bcl2tm1Sjk/Bcl2tm1Sjk | ||||||||||||||||||||||||||||||||||||||||||||
Bcl2tm1Tsu/Bcl2tm1Tsu | ||||||||||||||||||||||||||||||||||||||||||||
Bcl2tm2.1Lbox/Bcl2tm2.1Lbox | ||||||||||||||||||||||||||||||||||||||||||||
Bcl2tm2.1Lbox/Bcl2+ | ||||||||||||||||||||||||||||||||||||||||||||
Bcl2tm1Irt/Bcl2tm1Irt Lyz2tm1(cre)Ifo/Lyz2+ (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 07/05/2024 MGI 6.24 |
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