Symbol Name ID |
Cd27
CD27 antigen MGI:88326 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Decreased lymphocyte proliferation in response to mitogen |
Decreased circulating antibody level |
Hemophagocytosis |
Persistent EBV viremia |
Lymphadenopathy |
Splenomegaly |
Hepatosplenomegaly |
Uveitis |
Recurrent pneumonia |
Sepsis |
Recurrent infections |
EBV meningitis |
Severe varicella zoster infection |
EBV encephalitis |
Disease(s) Associated with CD27 | ||||||||||||||
lymphoproliferative syndrome 2 |
Mouse Phenotypes | immune system phenotype |
increased T cell apoptosis |
abnormal leukopoiesis |
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number |
decreased regulatory T cell number |
increased leukocyte cell number |
abnormal spleen morphology |
abnormal T cell physiology |
abnormal CD4-positive, alpha-beta T cell physiology |
abnormal cytotoxic T cell physiology |
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Availability | Mouse Genotype | ||||||||||
Cd27em1(IMPC)Ccpcz/Cd27em1(IMPC)Ccpcz | |||||||||||
Cd27tm1Jbo/Cd27tm1Jbo | * |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 07/05/2024 MGI 6.24 |
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