Symbol Name ID |
Cd3g
CD3 antigen, gamma polypeptide MGI:88333 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Chronic decreased circulating IgG2 |
Autoimmune hemolytic anemia |
Decreased proportion of CD8-positive T cells |
T lymphocytopenia |
Abnormal B cell morphology |
Recurrent gastroenteritis |
Recurrent otitis media |
Eczematoid dermatitis |
Chronic oral candidiasis |
Immunodeficiency |
Recurrent respiratory infections |
Disease(s) Associated with CD3G | |||||||||||
immunodeficiency 17 |
Mouse Phenotypes | immune system phenotype |
increased T cell apoptosis |
abnormal T cell proliferation |
thymus hypoplasia |
decreased thymocyte number |
abnormal T cell differentiation |
decreased CD8-positive, alpha-beta T cell number |
spleen hypoplasia |
abnormal T cell physiology |
abnormal CD8-positive, alpha-beta T cell physiology |
decreased cytotoxic T cell cytolysis |
abnormal T cell activation |
lymph node hypoplasia |
abnormal response to infection |
|
Availability | Mouse Genotype | ||||||||||||||
Cd3gtm1.1Cage/Cd3gtm1.1Cage | |||||||||||||||
Cd3gtm1Amk/Cd3gtm1Amk | |||||||||||||||
Cd3gtm2Amk/Cd3gtm2Amk | * |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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