Symbol Name ID |
Ercc1
excision repair cross-complementing rodent repair deficiency, complementation group 1 MGI:95412 |
Darker colors indicate more annotations |
Human Phenotypes | Increased circulating IgA concentration |
Increased circulating IgG concentration |
Decreased circulating antibody concentration |
Paraproteinemia |
Acute lymphoblastic leukemia |
T-cell acute lymphoblastic leukemias |
Acute myeloid leukemia |
Lymphadenopathy |
Splenomegaly |
Hepatosplenomegaly |
Peritoneal abscess |
Disease(s) Associated with ERCC1 | |||||||||||
acute lymphoblastic leukemia | |||||||||||
acute myeloid leukemia | |||||||||||
multiple myeloma | |||||||||||
pancreatic cancer |
Mouse Phenotypes | decreased B cell proliferation |
abnormal class switch recombination |
abnormal spleen morphology |
spleen hypoplasia |
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Availability | Mouse Genotype | ||||
Ercc1tm1Jhjh/Ercc1tm1Jhjh | |||||
Ercc1tm2Jhjh/Ercc1tm2Jhjh |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/03/2024 MGI 6.24 |
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