Symbol Name ID |
H2-K1
histocompatibility 2, K1, K region MGI:95904 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Eosinophilia |
Increased T cell count |
Leukopenia |
Keratoconjunctivitis sicca |
Abnormal lymph node morphology |
Lymphadenopathy |
Hepatosplenomegaly |
Helicobacter pylori infection |
Uveitis |
Iridocyclitis |
Posterior uveitis |
Inflammatory abnormality of the eye |
Epididymitis |
Erythema nodosum |
Psoriasiform dermatitis |
Maculopapular exanthema |
Autoimmunity |
Asthma |
Disease(s) Associated with HLA-A | ||||||||||||||||||
pre-eclampsia | ||||||||||||||||||
Disease(s) Associated with HLA-B | ||||||||||||||||||
asthma | ||||||||||||||||||
Behcet's disease | ||||||||||||||||||
birdshot chorioretinopathy | ||||||||||||||||||
sarcoidosis | ||||||||||||||||||
Disease(s) Associated with HLA-C | ||||||||||||||||||
psoriasis 1 | ||||||||||||||||||
Disease(s) Associated with HLA-G | ||||||||||||||||||
asthma |
Mouse Phenotypes | immune system phenotype |
decreased immature NK cell number |
decreased mature NK cell number |
decreased NK cell number |
increased NK cell number |
increased CD4-positive, alpha-beta T cell number |
decreased CD8-positive, alpha-beta T cell number |
decreased gamma-delta T cell number |
decreased activated T cell number |
abnormal CD8-positive, alpha beta T cell morphology |
impaired natural killer cell mediated cytotoxicity |
abnormal CD4-positive, alpha-beta T cell physiology |
abnormal cytotoxic T cell physiology |
abnormal T cell activation |
abnormal memory T cell physiology |
decreased macrophage nitric oxide production |
abnormal cytokine level |
abnormal immune system physiology |
decreased interferon-gamma secretion |
decreased susceptibility to autoimmune diabetes |
increased susceptibility to experimental autoimmune encephalomyelitis |
increased autoantibody level |
increased anti-nuclear antigen antibody level |
spinal cord inflammation |
myositis |
abnormal innate immunity |
increased susceptibility to bacterial infection |
decreased susceptibility to parasitic infection induced morbidity/mortality |
increased susceptibility to Herpesvirales infection |
increased response to antigen |
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Availability | Mouse Genotype | ||||||||||||||||||||||||||||||
H2-D1b-em1Dvs/H2-D1b-em1Dvs | |||||||||||||||||||||||||||||||
H2-D1b-em2Dvs/H2-D1b-em2Dvs | |||||||||||||||||||||||||||||||
H2-D1b-em3Dvs/H2-D1b-em3Dvs | |||||||||||||||||||||||||||||||
H2-D1b-em4Dvs/H2-D1b-em4Dvs | |||||||||||||||||||||||||||||||
H2-D1bm14/H2-D1bm14 | |||||||||||||||||||||||||||||||
H2-K1b-tm1Bpe/H2-K1b-tm1Bpe | |||||||||||||||||||||||||||||||
H2-K1d-em4Dvs/H2-K1d-em4Dvs | |||||||||||||||||||||||||||||||
H2-K1d-em5Dvs/H2-K1d-em5Dvs | |||||||||||||||||||||||||||||||
H2-K1d-em7Dvs/H2-K1d-em7Dvs | |||||||||||||||||||||||||||||||
H2-M3tm1Crw/H2-M3tm1Crw | |||||||||||||||||||||||||||||||
H2-Q10tm1.1(KOMP)Mbp/H2-Q10tm1.1(KOMP)Mbp | |||||||||||||||||||||||||||||||
H2-T23tm1Cant/H2-T23tm1Cant | |||||||||||||||||||||||||||||||
H2-T23tm3Cant/H2-T23tm3Cant | |||||||||||||||||||||||||||||||
Tg(CKMM-tTA)A3Rhvh/0 Tg(tetO-H2-K1)#Papl/0 |
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Tg(H2-Ld)LoxNibl/0 | |||||||||||||||||||||||||||||||
Tg(Camk2a-cre)2Gsc/0 Tg(H2-Ld)LoxNibl/0 (conditional) |
* |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 06/12/2024 MGI 6.13 |
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