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Symbol Name ID |
Il1r2
interleukin 1 receptor, type II MGI:96546 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | immune system phenotype |
abnormal alpha-beta T cell number |
increased T follicular helper cell number |
increased CD4-positive, alpha-beta T cell number |
abnormal CD8-positive, alpha-beta T cell number |
increased spleen germinal center size |
increased IgG level |
abnormal T cell physiology |
abnormal macrophage physiology |
increased macrophage cytokine production |
increased circulating interleukin-1 alpha level |
increased circulating interleukin-6 level |
abnormal adaptive immunity |
increased susceptibility to induced arthritis |
increased inflammatory response |
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| Availability | Mouse Genotype | |||||||||||||||
| Il1r2tm1.2Mchc/Il1r2tm1.2Mchc | ||||||||||||||||
| Il1r2tm1Yiw/Il1r2tm1Yiw | * | |||||||||||||||
| Foxp3tm9(EGFP/cre/ERT2)Ayr/Foxp3+ Il1r2tm1.1Mchc/Il1r2tm1.1Mchc (conditional) |
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| Gt(ROSA)26Sortm1(cre/ERT)Nat/Gt(ROSA)26Sor+ Il1r2tm1.1Mchc/Il1r2tm1.1Mchc (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 06/12/2024 MGI 6.13 |
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