Symbol Name ID |
Itgb3
integrin beta 3 MGI:96612 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Increased circulating IgA concentration |
Increased circulating IgE concentration |
Leukocytosis |
Acute myeloid leukemia |
Splenomegaly |
Eczematoid dermatitis |
Platelet antibody positive |
Asthma |
Disease(s) Associated with ITGB3 | ||||||||
acute myeloid leukemia | ||||||||
asthma | ||||||||
autoimmune thrombocytopenic purpura | ||||||||
thrombocytopenia |
Mouse Phenotypes | immune system phenotype |
abnormal osteoclast differentiation |
impaired macrophage chemotaxis |
enlarged spleen |
decreased macrophage cell number |
decreased osteoclast cell number |
increased osteoclast cell number |
increased monocyte cell number |
abnormal osteoclast morphology |
increased IgG level |
abnormal macrophage physiology |
abnormal osteoclast physiology |
myositis |
dermatitis |
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Availability | Mouse Genotype | ||||||||||||||
Itgb3tm1Hyn/Itgb3tm1Hyn | * | ||||||||||||||
Itgb3tm1Hyn/Itgb3tm1.1Wlbcr Lyz2tm1(cre)Ifo/Lyz2+ (conditional) |
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Itgb3tm1Hyn/Itgb3tm1.1Wlbcr Tg(Pf4-icre)Q3Rsko/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/03/2024 MGI 6.24 |
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