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Symbol Name ID |
Pgd
phosphogluconate dehydrogenase MGI:97553 |
| Darker colors indicate more annotations |
| Mouse Phenotypes | enlarged spleen |
ear inflammation |
abnormal T cell differentiation |
decreased CD4-positive, alpha-beta T cell number |
decreased CD8-positive, alpha-beta T cell number |
increased T cell number |
abnormal alpha-beta T cell morphology |
abnormal CD4-positive helper T cell morphology |
abnormal CD8-positive, alpha beta T cell morphology |
increased IgA level |
increased IgD level |
increased IgE level |
increased IgG2a level |
increased IgG3 level |
increased IgM level |
abnormal CD8-positive, alpha-beta T cell physiology |
abnormal regulatory T cell physiology |
increased circulating interferon-gamma level |
increased circulating interleukin-17 level |
increased circulating interleukin-4 level |
increased circulating interleukin-5 level |
enlarged lymph nodes |
increased susceptibility to type I hypersensitivity reaction |
increased interferon-gamma secretion |
blepharitis |
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| Availability | Mouse Genotype | |||||||||||||||||||||||||
| Pgdtm1.1Pse/Pgdtm1.1Pse Tg(Cd4-cre)1Cwi/0 (conditional) |
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| Pgdtm1.1Pse/Pgdtm1.1Pse Foxp3tm4(YFP/icre)Ayr/Foxp3+ (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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