Symbol
Name
ID

Zfp36
zinc finger protein 36
MGI:99180

Phenotype annotations related to immune system

Darker colors indicate more annotations

Mouse Phenotypes

blood vessel inflammation

heart inflammation

abnormal thymus cortex morphology

abnormal thymus medulla morphology

thymus hypoplasia

enlarged spleen

increased spleen weight

spleen hyperplasia

increased neutrophil cell number

increased granulocyte number

decreased lymphocyte cell number

increased monocyte cell number

increased leukocyte cell number

abnormal macrophage physiology

increased circulating tumor necrosis factor level

enlarged lymph nodes

decreased susceptibility to experimental autoimmune encephalomyelitis

decreased susceptibility to induced arthritis

increased susceptibility to endotoxin shock

decreased inflammatory response

increased inflammatory response

conjunctivitis

arthritis

liver inflammation

alveolitis

dermatitis

Availability

Mouse Genotype

Zfp36^tm1Pjb/Zfp36^tm1Pjb

Zfp36^tm2.1Pjb/Zfp36^tm2.1Pjb

Zfp36^{tm1(KOMP)Vlcg}/Zfp36⁺

Zfp36^tm4.1Pjb/Zfp36^tm4.1Pjb
Lyz2^tm1(cre)Ifo/Lyz2⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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