Symbol Name ID |
Pik3ca
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha MGI:1206581 |
Darker colors indicate more annotations |
Mouse Phenotypes | increased mammary gland epithelial cell proliferation |
abnormal branching of the mammary ductal tree |
abnormal mammary gland epithelium morphology |
abnormal mammary gland duct morphology |
abnormal mammary duct terminal end bud morphology |
abnormal mammary gland myoepithelium morphology |
abnormal mammary gland stroma morphology |
increased mammary gland tumor incidence |
increased fibroadenoma incidence |
increased mammary adenocarcinoma incidence |
increased mammary adenoacanthoma incidence |
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Availability | Mouse Genotype | |||||||||||
Gt(ROSA)26Sortm1(Pik3ca*H1047R)Egan/Gt(ROSA)26Sor+ Tg(MMTV-cre)1Mam/0 (conditional) |
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Gt(ROSA)26Sortm1(Pik3ca*H1047R)Egan/Gt(ROSA)26Sor+ Tg(MMTV-cre)#Tfln/0 (conditional) |
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Pik3catm1.1Waph/Pik3ca+ Tg(MMTV-cre)#Mam/0 (conditional) |
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Pik3catm1Gne/Pik3ca+ Tg(MMTV-cre)1Mam/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 07/02/2024 MGI 6.13 |
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