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Symbol
Name
ID
Akt1
thymoma viral proto-oncogene 1
MGI:87986
Phenotype annotations related to integument
Darker colors indicate more annotations
Human Phenotypes
Breast carcinoma
Jaundice
Disease(s) Associated with AKT1
pancreatic cancer

Mouse Phenotypes
decreased keratinocyte proliferation
abnormal mammary gland duct morphology
mammary gland alveolar hyperplasia
abnormal mammary gland stroma morphology
mammary gland hyperplasia
thin hypodermis
underdeveloped hair follicles
epidermal hyperplasia
pallor
increased trichoepithelioma incidence
Availability Mouse Genotype
Akt1tm1Hem/Akt1tm1Hem
Akt1tm1.1Mjl/Akt1+
Tg(KRT5-Akt1*)Jmpa/0
Akt1tm1Mjl/Akt1+
Gt(ROSA)26Sortm1(cre/ERT)Nat/Gt(ROSA)26Sortm1(cre/ERT)Nat  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
07/02/2024
MGI 6.13
The Jackson Laboratory