|
Symbol Name ID |
Braf
Braf transforming gene MGI:88190 |
| Darker colors indicate more annotations |
| Human Phenotypes | Low posterior hairline |
Aplasia/Hypoplasia of the eyebrow |
Abnormal eyelash morphology |
Sparse or absent eyelashes |
Palmoplantar keratoderma |
Deep palmar crease |
Breast carcinoma |
Jaundice |
Sparse hair |
Slow-growing hair |
Brittle hair |
Fine hair |
Dystrophic fingernails |
Redundant skin |
Excessive wrinkled skin |
Hyperextensible skin |
Generalized hyperpigmentation |
Multiple cafe-au-lait spots |
Multiple lentigines |
Dry skin |
Hyperkeratosis |
Ichthyosis |
| Disease(s) Associated with BRAF | ||||||||||||||||||||||
| cardiofaciocutaneous syndrome | ||||||||||||||||||||||
| pancreatic cancer |
| Mouse Phenotypes | abnormal skin sebaceous gland morphology |
sparse hair |
ruffled hair |
long nails |
nail dystrophy |
skin lesions |
spontaneous skin ulceration |
abnormal dermal melanocyte morphology |
increased skin tumor incidence |
increased skin papilloma incidence |
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| Availability | Mouse Genotype | ||||||||||
| Braftm1Bbd/Braf+ | |||||||||||
| Braftm1Cpri/Braftm1Cpri Tg(Tyr-cre/ERT2)1Lru/0 (conditional) |
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| Braftm1Cpri/Braf+ Scn10atm2(cre)Jwo/Scn10a+ (conditional) |
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| Braftm1Mmcm/Braf+ Tg(Tyr-cre/ERT2)13Bos/0 (conditional) |
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| Braftm1Tumg/Braf+ Tg(CAG-cre)2Osb/0 (conditional) |
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| Braftm2Cpri/Braf+ Tg(CMV-cre)1Cgn/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 07/02/2024 MGI 6.13 |
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