Symbol Name ID |
Col1a1
collagen, type I, alpha 1 MGI:88467 |
Darker colors indicate more annotations |
Human Phenotypes | Bruising susceptibility |
Palmoplantar hyperkeratosis |
Hyperhidrosis |
Cutis laxa |
Hyperextensible skin |
Soft, doughy skin |
Poor wound healing |
Atrophic scars |
Thin skin |
Skin ulcer |
Pallor |
Disease(s) Associated with COL1A1 | |||||||||||
aggressive periodontitis | |||||||||||
beta thalassemia | |||||||||||
dentinogenesis imperfecta | |||||||||||
Ehlers-Danlos syndrome arthrochalasia type 1 | |||||||||||
osteogenesis imperfecta | |||||||||||
osteogenesis imperfecta type 1 | |||||||||||
osteogenesis imperfecta type 2 |
Mouse Phenotypes | abnormal coat/hair pigmentation |
focal hair loss |
abnormal cutaneous collagen fibril morphology |
abnormal dermal layer morphology |
thick dermal layer |
decreased skin tensile strength |
|
Availability | Mouse Genotype | ||||||
Col1a1tm1Jae/Col1a1tm1Jae | |||||||
Col1a1Aga2/Col1a1+ | |||||||
Col1a1M1Jrt/Col1a1+ | |||||||
Col1a1Mov13/Col1a1+ | |||||||
Col1a1tm1Jae/Col1a1+ |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 08/02/2024 MGI 6.24 |
|
|