Symbol Name ID |
Itgb2
integrin beta 2 MGI:96611 |
* | Aspects of the system are reported to show a normal phenotype. |
! | Indicates phenotype varies with strain background. |
Darker colors indicate more annotations |
Human Phenotypes | Perianal abscess |
Recurrent skin infections |
Chronic mucocutaneous candidiasis |
Chronic oral candidiasis |
Nail dystrophy |
Poor wound healing |
Skin ulcer |
Pyoderma gangrenosum |
Disease(s) Associated with ITGB2 | ||||||||
leukocyte adhesion deficiency | ||||||||
leukocyte adhesion deficiency 1 |
Mouse Phenotypes | integument phenotype |
dermatitis |
alopecia |
abnormal hair follicle dermal papilla morphology |
abnormal dermal layer morphology |
mixed cellular infiltration to dermis |
abnormal epidermal layer morphology |
hyperkeratosis |
orthokeratosis |
parakeratosis |
acanthosis |
epidermal hyperplasia |
reddish skin |
scaly skin |
spontaneous skin ulceration |
abnormal skin condition |
psoriasis |
|
Availability | Mouse Genotype | |||||||||||||||||
Itgb2tm1Bay/Itgb2tm1Bay | *! | ! | ! | |||||||||||||||
Itgb2tm2Bay/Itgb2tm2Bay | * | |||||||||||||||||
Itgb2tm1Bay/Itgb2tm2Bay | *! | ! | ! |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 07/05/2024 MGI 6.24 |
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