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Symbol
Name
ID
Ptgs2
prostaglandin-endoperoxide synthase 2
MGI:97798
Phenotype annotations related to integument
Darker colors indicate more annotations
Human Phenotypes
Elevated sweat chloride
Breast carcinoma
Jaundice
Erythema nodosum
Maculopapular exanthema
Alopecia
Abnormal skin morphology
Hyperpigmentation of the skin
Hypopigmentation of the skin
Skin nodule
Subcutaneous nodule
Skin plaque
Salty tasting skin
Disease(s) Associated with PTGS2
cystic fibrosis
pancreatic cancer
sarcoidosis

Mouse Phenotypes
abnormal keratinocyte differentiation
sebaceous gland hyperplasia
abnormal coat/ hair morphology
abnormal coat appearance
alopecia
sparse hair
coarse hair
greasy coat
abnormal nail morphology
long toenails
abnormal hair follicle morphology
abnormal hair follicle development
abnormal hair follicle orientation
decreased hair follicle number
abnormal hair cycle
abnormal dermal layer morphology
hyperkeratosis
epidermal hyperplasia
thin skin
increased skin papilloma incidence
Availability Mouse Genotype
Ptgs2tm1Unc/Ptgs2tm1Unc
Tg(K5-Ptgs2)675Kmd/Tg(K5-Ptgs2)675Kmd
Tg(K5-Ptgs2)19Kmd/0
Tg(K5-Ptgs2)667Kmd/0
Tg(K5-Ptgs2)675Kmd/0

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
07/05/2024
MGI 6.24
The Jackson Laboratory