Symbol Name ID |
Shh
sonic hedgehog MGI:98297 |
Darker colors indicate more annotations |
Human Phenotypes | Highly arched eyebrow |
Synophrys |
Thick eyebrow |
Nail dysplasia |
Disease(s) Associated with SHH | ||||
holoprosencephaly | ||||
polydactyly |
Mouse Phenotypes | decreased keratinocyte proliferation |
alopecia |
abnormal hair shaft morphology |
abnormal hair follicle morphology |
abnormal hair follicle development |
absent hair follicle inner root sheath |
abnormal hair follicle orientation |
absent hair follicles |
absent vibrissae |
abnormal dermal layer morphology |
abnormal dermis papillary layer morphology |
abnormal epidermal layer morphology |
epidermal hyperplasia |
thick epidermis |
shiny skin |
tight skin |
translucent skin |
increased basal cell carcinoma incidence |
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Availability | Mouse Genotype | ||||||||||||||||||
Shhtm1Amc/Shhtm1Amc | |||||||||||||||||||
Tg(KRT14-Shh)#Cobm/0 | |||||||||||||||||||
Shhtm1Amc/Shhtm2Amc Tg(KRT14-cre)1Amc/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 06/12/2024 MGI 6.13 |
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