Symbol Name ID |
Lmx1b
LIM homeobox transcription factor 1 beta MGI:1100513 |
Darker colors indicate more annotations |
Human Phenotypes | Abnormal digit morphology |
Clinodactyly of the 5th finger |
Absent distal interphalangeal creases |
Contracture of the distal interphalangeal joint of the fingers |
Proximal finger joint hyperextensibility |
Abnormal femur morphology |
Disproportionate prominence of the femoral medial condyle |
Abnormal tibia morphology |
Patellar aplasia |
Patellar hypoplasia |
Dislocated radial head |
Hypoplastic radial head |
Elongated radius |
Achilles tendon contracture |
Equinovarus deformity |
Pes planus |
Talipes calcaneovalgus |
Talipes calcaneovarus |
Talipes equinovalgus |
Talipes equinovarus |
Abnormality of the knee |
Abnormal patella morphology |
Patellar dislocation |
Knee flexion contracture |
Knee joint hypermobility |
Quadriceps aplasia |
Biceps aplasia |
Triceps aplasia |
Abnormality of the elbow |
Cubitus valgus |
Elbow flexion contracture |
Limited elbow extension |
Limited pronation/supination of forearm |
Disease(s) Associated with LMX1B | |||||||||||||||||||||||||||||||||
nail-patella syndrome |
Mouse Phenotypes | abnormal foot pad morphology |
absent ulna |
abnormal ankle joint morphology |
absent patella |
abnormal metacarpal bone morphology |
abnormal limb development |
abnormal limb position |
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Availability | Mouse Genotype | |||||||
Lmx1bIcst/Lmx1bIcst | ||||||||
Lmx1btm1Rjo/Lmx1btm1Rjo | ||||||||
Lmx1btm3(cre/ERT2)Rjo/Lmx1btm3(cre/ERT2)Rjo | ||||||||
Gt(ROSA)26Sortm1(CAG-Lmx1b,ALPP)Rjo/Gt(ROSA)26Sor+ Sox9tm3(cre)Crm/Sox9+ (conditional) |
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Gt(ROSA)26Sortm1(CAG-Lmx1b,ALPP)Rjo/Gt(ROSA)26Sor+ Tg(Prrx1-cre)1Cjt/0 (conditional) |
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Lmx1btm1Rjo/Lmx1btm1Zfc Sox9tm3(cre)Crm/Sox9+ (conditional) |
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Lmx1btm1Rjo/Lmx1btm1Zfc Tg(Prrx1-cre)1Cjt/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/27/2024 MGI 6.24 |
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