Symbol Name ID |
Mfn2
mitofusin 2 MGI:2442230 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Tapered finger |
Paresis of extensor muscles of the big toe |
Hammertoe |
Abnormal foot morphology |
Pes cavus |
Talipes equinovarus |
Increased laxity of ankles |
Areflexia of lower limbs |
Absent patellar reflexes |
Absent Achilles reflex |
Distal lower limb muscle weakness |
Hand muscle weakness |
Triceps weakness |
Upper limb amyotrophy |
Limb muscle weakness |
Foot dorsiflexor weakness |
Quadriceps muscle weakness |
Abnormality of the hand |
Disease(s) Associated with MFN2 | ||||||||||||||||||
Charcot-Marie-Tooth disease type 2A2A | ||||||||||||||||||
Charcot-Marie-Tooth disease type 2A2B | ||||||||||||||||||
Charcot-Marie-Tooth disease type 6 | ||||||||||||||||||
multiple symmetric lipomatosis |
Mouse Phenotypes | limbs/digits/tail phenotype |
abnormal autopod morphology |
abnormal hindlimb morphology |
abnormal tail morphology |
short tail |
kinked tail |
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Availability | Mouse Genotype | ||||||
Tg(Mnx1-Mfn2*T105M,-EGFP)1Dcc/Tg(Mnx1-Mfn2*T105M,-EGFP)1Dcc | |||||||
Tg(Mnx1-Mfn2*T105M,-EGFP)1Dcc/0 | * |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/03/2024 MGI 6.24 |
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