Symbol Name ID |
Jag1
jagged 1 MGI:1095416 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Hepatomegaly |
Cirrhosis |
Reduced number of intrahepatic bile ducts |
Cholestasis |
Cholestatic liver disease |
Prolonged neonatal jaundice |
Hepatocellular carcinoma |
Disease(s) Associated with JAG1 | |||||||
Alagille syndrome |
Mouse Phenotypes | liver/biliary system phenotype |
abnormal liver vasculature morphology |
liver hemorrhage |
abnormal bile duct morphology |
abnormal bile duct development |
abnormal cholangiocyte morphology |
bile duct proliferation |
dilated bile duct |
abnormal liver morphology |
hepatic necrosis |
abnormal bile secretion |
cholestasis |
abnormal liver physiology |
jaundice |
|
Availability | Mouse Genotype | ||||||||||||||
Jag1Ndr/Jag1Ndr | |||||||||||||||
Jag1tm1Frad/Jag1tm1Frad Tg(Tagln-cre)1Her/0 (conditional) |
|||||||||||||||
Jag1tm1Frad/Jag1tm1Frad Tg(Cdh5-cre)7Mlia/0 (conditional) |
* | ||||||||||||||
Jag1tm1Grid/Jag1tm1.1Loo Tg(Alb1-cre)1Khk/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 07/05/2024 MGI 6.24 |
|
|