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Symbol
Name
ID

Sod2
superoxide dismutase 2, mitochondrial
MGI:98352

Phenotype annotations related to liver/biliary system

*	Aspects of the system are reported to show a normal phenotype.
!	Indicates phenotype varies with strain background.
	Darker colors indicate more annotations

Human Phenotypes	Hepatic steatosis	Hepatosplenomegaly	Micronodular cirrhosis	Subacute progressive viral hepatitis	Extrahepatic cholestasis	Jaundice	Neoplasm of the liver	Hepatocellular carcinoma
Disease(s) Associated with SOD2	Hepatic steatosis	Hepatosplenomegaly	Micronodular cirrhosis	Subacute progressive viral hepatitis	Extrahepatic cholestasis	Jaundice	Neoplasm of the liver	Hepatocellular carcinoma
hepatocellular carcinoma
metabolic dysfunction-associated steatotic liver disease
pancreatic cancer

Mouse Phenotypes		liver/biliary system phenotype	increased hepatocyte apoptosis	increased liver weight	abnormal hepatocyte morphology	hepatic steatosis	abnormal liver physiology
Availability	Mouse Genotype	liver/biliary system phenotype	increased hepatocyte apoptosis	increased liver weight	abnormal hepatocyte morphology	hepatic steatosis	abnormal liver physiology
	Sod2^tm1Cje/Sod2^tm1Cje	*!				!
	Sod2^tm1Leb/Sod2^tm1Leb
	Sod2^tm1Cje/Sod2⁺
	Sod2^tm1Shs/Sod2^tm1Shs (conditional)	*

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 07/05/2024 MGI 6.24