Symbol Name ID |
Tnf
tumor necrosis factor MGI:104798 |
* | Aspects of the system are reported to show a normal phenotype. |
! | Indicates phenotype varies with strain background. |
Darker colors indicate more annotations |
Human Phenotypes | Death in infancy |
Miscarriage |
Sudden cardiac death |
Disease(s) Associated with TNF | |||
coronary artery disease | |||
Gaucher's disease | |||
systemic lupus erythematosus |
Mouse Phenotypes | mortality/aging |
increased susceptibility to bacterial infection induced morbidity/mortality |
decreased susceptibility to induced morbidity/mortality |
increased susceptibility to induced morbidity/mortality |
premature death |
lethality throughout fetal growth and development, complete penetrance |
prenatal lethality, complete penetrance |
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Availability | Mouse Genotype | |||||||
Lta/Tnftm1Eug/Lta/Tnftm1Eug | ||||||||
TnfBpsm1/TnfBpsm1 | *! | |||||||
Tnfem4Boui/Tnfem4Boui | ||||||||
Tnfem5Boui/Tnfem5Boui | ||||||||
TnfR8H/TnfR8H | ||||||||
Tnftm2Gkl/Tnftm2Gkl | ||||||||
TnfBpsm1/Tnf+ | *! | ! | ||||||
Tnfem4Boui/Tnf+ | ||||||||
Tg(SFTPC-Tnf)2Pva/0 | ||||||||
Tg(Myh6-Tnf)1Brgi/? | ||||||||
Tg(Myh6-Tnf)2Brgi/? | ||||||||
Tnftm1.1Sned/Tnftm1.1Sned Lyz2tm1(cre)Ifo/Lyz2+ (conditional) |
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Tnftm1.1Sned/Tnftm1.1Sned Tg(Cd4-cre)1Cwi/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/03/2024 MGI 6.24 |
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