Symbol Name ID |
Ldb3
LIM domain binding 3 MGI:1344412 |
Darker colors indicate more annotations |
Human Phenotypes | Calf muscle pseudohypertrophy |
Distal lower limb muscle weakness |
Proximal muscle weakness in upper limbs |
EMG: myopathic abnormalities |
EMG: neuropathic changes |
Difficulty running |
Muscle stiffness |
Progressive distal muscle weakness |
Progressive muscle weakness |
Progressive proximal muscle weakness |
Autophagic vacuoles |
Muscle fiber splitting |
Distal amyotrophy |
Myofibrillar myopathy |
Rhabdomyolysis |
Disease(s) Associated with LDB3 | |||||||||||||||
distal myopathy | |||||||||||||||
myofibrillar myopathy 4 |
Mouse Phenotypes | abnormal myocardium layer morphology |
abnormal myocardial fiber morphology |
dilated cardiomyopathy |
decreased cardiac muscle contractility |
abnormal Z line morphology |
skeletal muscle fiber atrophy |
increased variability of skeletal muscle fiber size |
abnormal skeletal muscle morphology |
muscle weakness |
myopathy |
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Availability | Mouse Genotype | ||||||||||
Ldb3tm1Chen/Ldb3tm1Chen | |||||||||||
Ldb3tm2Chen/Ldb3tm2Chen | |||||||||||
Ldb3tm3Chen/Ldb3tm3Chen | |||||||||||
Ldb3tm6.2Chen/Ldb3tm6.2Chen | |||||||||||
Ldb3tm4Chen/Ldb3tm4Chen Myl2tm1(cre)Krc/Myl2+ (conditional) |
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Ldb3tm4Chen/Ldb3tm4Chen A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+ (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/21/2024 MGI 6.24 |
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