Symbol Name ID |
Bag3
BCL2-associated athanogene 3 MGI:1352493 |
Darker colors indicate more annotations |
Human Phenotypes | Facial palsy |
Knee flexion contracture |
Scapular winging |
Lower limb muscle weakness |
EMG: myopathic abnormalities |
Easy fatigability |
Axial muscle weakness |
Diaphragmatic paralysis |
Distal muscle weakness |
Generalized muscle weakness |
Proximal muscle weakness |
Generalized amyotrophy |
Muscular dystrophy |
Myofibrillar myopathy |
Disease(s) Associated with BAG3 | ||||||||||||||
myofibrillar myopathy 6 |
Mouse Phenotypes | myocardial fiber degeneration |
dilated cardiomyopathy |
decreased cardiac muscle contractility |
increased cardiomyocyte apoptosis |
abnormal Z line morphology |
skeletal muscle fiber degeneration |
abnormal skeletal muscle morphology |
|
Availability | Mouse Genotype | |||||||
Bag3Gt(OST16086)Lex/Bag3Gt(OST16086)Lex | ||||||||
Bag3tm1c(EUCOMM)Hmgu/Bag3tm1c(EUCOMM)Hmgu Tg(Myhca-cre)1Abel/0 (conditional) |
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Bag3tm1c(EUCOMM)Hmgu/Bag3tm1.1Chen Tg(Myhca-cre)1Abel/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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