Symbol
Name
ID

Sgca
sarcoglycan, alpha (dystrophin-associated glycoprotein)
MGI:894698

Phenotype annotations related to muscle

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Achilles tendon contracture	Calf muscle pseudohypertrophy	Scapular winging	Difficulty climbing stairs	Frequent falls	Proximal muscle weakness	Gowers sign	Muscular dystrophy
Disease(s) Associated with SGCA
autosomal recessive limb-girdle muscular dystrophy type 2D

Mouse Phenotypes

muscle phenotype

cardiac muscle necrosis

cardiomyopathy

increased extensor digitorum longus weight

increased soleus weight

abnormal muscle fiber morphology

abnormal sarcolemma morphology

abnormal skeletal muscle fiber morphology

centrally nucleated skeletal muscle fibers

increased muscle weight

abnormal skeletal muscle morphology

skeletal muscle fibrosis

calcified muscle

dystrophic muscle

abnormal muscle physiology

abnormal muscle contractility

impaired skeletal muscle contractility

Availability

Mouse Genotype

Sgca^tm1Eeng/Sgca^tm1Eeng

Sgca^tm1Isrd/Sgca^tm1Isrd

Sgca^tm1Kcam/Sgca^tm1Kcam

Sgca^tm2Kcam/Sgca^tm2Kcam

Sgca^tm2Kcam/Sgca^tm2Kcam
Tg(Ckmm-cre)5Khn/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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