Symbol Name ID |
Cdk5r1
cyclin dependent kinase 5, regulatory subunit 1 MGI:101764 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Mouse Phenotypes | nervous system phenotype |
increased susceptibility to pharmacologically induced seizures |
seizures |
abnormal axon extension |
abnormal forebrain development |
thin cortical plate |
abnormal subplate morphology |
abnormal olfactory bulb development |
dilated lateral ventricle |
decreased corpus callosum size |
abnormal forebrain morphology |
abnormal striatum morphology |
decreased striatum size |
abnormal hippocampus morphology |
abnormal dentate gyrus morphology |
abnormal hippocampus layer morphology |
abnormal hippocampus granule cell morphology |
abnormal hippocampus pyramidal cell morphology |
abnormal cerebral cortex morphology |
abnormal cerebral cortex pyramidal cell morphology |
abnormal stratification in cerebral cortex |
abnormal cerebellum morphology |
ectopic Purkinje cell |
delaminated Purkinje cell layer |
ectopic cerebellar granule cells |
abnormal cerebellar molecular layer |
abnormal innervation |
impaired synaptic plasticity |
abnormal excitatory postsynaptic potential |
reduced long-term potentiation |
abnormal long-term depression |
absent long-term depression |
reduced long-term depression |
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Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||
Cdk5r1tm1Ivi/Cdk5r1tm1Ivi | ||||||||||||||||||||||||||||||||||
Cdk5r1tm1Lht/Cdk5r1tm1Lht | ||||||||||||||||||||||||||||||||||
Cdk5r1tm1Ohsh/Cdk5r1tm1Ohsh | ||||||||||||||||||||||||||||||||||
Cdk5r1tm2.1Lht/Cdk5r1tm2.1Lht | ||||||||||||||||||||||||||||||||||
Cdk5r1tm2Ohsh/Cdk5r1tm2Ohsh Tg(Pcp2-cre)1Amc/0 (conditional) |
* |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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