Symbol Name ID |
Reln
reelin MGI:103022 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Microcephaly |
Primary microcephaly |
Dysphagia |
Cerebral calcification |
Hypoplasia of the pons |
Lissencephaly |
4-layered lissencephaly |
Microlissencephaly |
Thick cerebral cortex |
Agenesis of corpus callosum |
Hypoplasia of the corpus callosum |
Cerebellar hypoplasia |
Cerebellar atrophy |
Abnormality of neuronal migration |
EEG abnormality |
Abnormal nonverbal communicative behavior |
Delayed speech and language development |
Lack of spontaneous play |
Impaired ability to form peer relationships |
Autism |
Inflexible adherence to routines |
Motor stereotypy |
Restrictive behavior |
Intellectual disability |
Global developmental delay |
Profound global developmental delay |
Severe global developmental delay |
Seizure |
Focal sensory seizure with auditory features |
Generalized-onset seizure |
Disease(s) Associated with RELN | ||||||||||||||||||||||||||||||
autistic disorder | ||||||||||||||||||||||||||||||
familial temporal lobe epilepsy 7 | ||||||||||||||||||||||||||||||
Norman-Roberts syndrome |
Mouse Phenotypes | nervous system phenotype |
abnormal neuron differentiation |
abnormal axon extension |
abnormal neuronal migration |
abnormal cortical marginal zone morphology |
abnormal cerebellum development |
absent cerebellar foliation |
abnormal cerebellum external granule cell layer morphology |
abnormal rostral migratory stream morphology |
abnormal ventral striatum morphology |
abnormal entorhinal cortex morphology |
abnormal hippocampus morphology |
abnormal hippocampus CA1 region morphology |
abnormal hippocampus CA2 region morphology |
abnormal dentate gyrus morphology |
abnormal hippocampus layer morphology |
abnormal hippocampus granule cell layer |
abnormal hippocampus pyramidal cell layer |
abnormal cerebral cortex morphology |
abnormal stratification in cerebral cortex |
abnormal olfactory bulb morphology |
abnormal olfactory bulb granule cell layer morphology |
abnormal olfactory cortex morphology |
abnormal cerebellum morphology |
abnormal cerebellar cortex morphology |
abnormal cerebellar Purkinje cell layer |
abnormal Purkinje cell morphology |
Purkinje cell degeneration |
decreased Purkinje cell number |
ectopic Purkinje cell |
delaminated Purkinje cell layer |
abnormal cerebellar granule layer morphology |
delaminated cerebellar granule layer |
small cerebellum |
abnormal postnatal subventricular zone morphology |
abnormal sensory neuron innervation pattern |
decreased dopaminergic neuron number |
abnormal retina rod bipolar cell morphology |
abnormal prepulse inhibition |
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Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||||||
Relnrl-2J/Relnrl-2J | ||||||||||||||||||||||||||||||||||||||||
Relnrl-4J/Relnrl-4J | ||||||||||||||||||||||||||||||||||||||||
Relnrl-5J/Relnrl-5J | ||||||||||||||||||||||||||||||||||||||||
Relnrl-6J/Relnrl-6J | ||||||||||||||||||||||||||||||||||||||||
Relnrl-7J/Relnrl-7J | ||||||||||||||||||||||||||||||||||||||||
Relnrl-8J/Relnrl-8J | ||||||||||||||||||||||||||||||||||||||||
Relnrl-Alb/Relnrl-Alb | ||||||||||||||||||||||||||||||||||||||||
Relnrl-od/Relnrl-od | ||||||||||||||||||||||||||||||||||||||||
Relnrl-Orl/Relnrl-Orl | ||||||||||||||||||||||||||||||||||||||||
Relnrl-tg/Relnrl-tg | ||||||||||||||||||||||||||||||||||||||||
Relnrl/Relnrl | ||||||||||||||||||||||||||||||||||||||||
Relnrl/Relnrl Tg(Mbp-MAPT/lacZ)#aCaw/Tg(Mbp-MAPT/lacZ)#aCaw |
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Relntm1.1Mhat/Relntm1.1Mhat | * | |||||||||||||||||||||||||||||||||||||||
Relnrl/Reln+ | * |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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