Symbol Name ID |
Atrx
ATRX, chromatin remodeler MGI:103067 |
Darker colors indicate more annotations |
Human Phenotypes | Microcephaly |
Aganglionic megacolon |
Infectious encephalitis |
Spasticity |
Spastic paraplegia |
Cerebral cortical atrophy |
Agenesis of corpus callosum |
Cerebral atrophy |
Aphasia |
Depression |
Atypical behavior |
Autism |
Motor stereotypy |
Self-injurious behavior |
Intellectual disability |
Abnormality of movement |
Global developmental delay |
Profound global developmental delay |
Seizure |
Bilateral tonic-clonic seizure |
Disease(s) Associated with ATRX | ||||||||||||||||||||
alpha thalassemia-X-linked intellectual disability syndrome |
Mouse Phenotypes | absent dentate gyrus |
decreased hippocampus pyramidal cell number |
loss of hippocampal neurons |
loss of cortex neurons |
decreased amacrine cell number |
abnormal retina horizontal cell morphology |
reduced long-term potentiation |
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Availability | Mouse Genotype | |||||||
Atrxtm1Enl/Atrxtm1Enl | ||||||||
Atrxtm1Rjg/Y Foxg1tm1(cre)Skm/Foxg1+ (conditional) |
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Atrxtm1Rjg/Y Tg(Nes-cre)2472Pick/0 (conditional) |
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Atrxtm1Rjg/Y Tg(Pax6-cre,GFP)2Pgr/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 07/05/2024 MGI 6.24 |
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