Symbol Name ID |
Rps6ka3
ribosomal protein S6 kinase polypeptide 3 MGI:104557 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Microcephaly |
Ventriculomegaly |
Delayed speech and language development |
Intellectual disability |
Intellectual disability, mild |
Global developmental delay |
Motor delay |
Seizure |
Disease(s) Associated with RPS6KA3 | ||||||||
Coffin-Lowry syndrome | ||||||||
non-syndromic X-linked intellectual disability 19 |
Mouse Phenotypes | nervous system phenotype |
abnormal dendritic spine morphology |
abnormal synapse morphology |
abnormal postsynaptic density morphology |
abnormal CNS synaptic transmission |
short excitatory postsynaptic current decay time |
abnormal excitatory postsynaptic potential |
reduced AMPA-mediated synaptic currents |
|
Availability | Mouse Genotype | ||||||||
Rps6ka3tm1.1Kry/Rps6ka3tm1.1Kry | * | ||||||||
Rps6ka3tm1.1Kry/Rps6ka3+ | * |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/03/2024 MGI 6.24 |
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