Symbol Name ID |
Cdkn1b
cyclin dependent kinase inhibitor 1B MGI:104565 |
Darker colors indicate more annotations |
Human Phenotypes | Elevated circulating growth hormone concentration |
Pituitary adenoma |
Carcinoid tumor |
Pancreatic endocrine tumor |
Disease(s) Associated with CDKN1B | ||||
multiple endocrine neoplasia type 4 |
Mouse Phenotypes | abnormal neuron differentiation |
abnormal neuronal migration |
increased pituitary gland weight |
enlarged pituitary gland |
pituitary gland hyperplasia |
abnormal pituitary intermediate lobe morphology |
pituitary intermediate lobe hyperplasia |
increased pituitary gland tumor incidence |
increased pituitary adenoma incidence |
increased cochlear hair cell number |
increased cochlear inner hair cell number |
increased cochlear outer hair cell number |
increased brain weight |
abnormal epithalamus morphology |
abnormal hippocampus morphology |
abnormal cerebral cortex morphology |
abnormal Muller cell morphology |
increased amacrine cell number |
abnormal retina photoreceptor morphology |
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Availability | Mouse Genotype | |||||||||||||||||||
Cdkn1btm1Ako/Cdkn1btm1Ako | ||||||||||||||||||||
Cdkn1btm1Kin/Cdkn1btm1Kin | ||||||||||||||||||||
Cdkn1btm1Mlf/Cdkn1btm1Mlf | ||||||||||||||||||||
Cdkn1btm3Mlf/Cdkn1btm3Mlf | ||||||||||||||||||||
Cdkn1btm1Mlf/Cdkn1b+ | ||||||||||||||||||||
Cdkn1btm2Mlf/Cdkn1btm2Mlf Tg(Pomc1-cre)1Mlf/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 07/05/2024 MGI 6.24 |
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