Symbol Name ID |
Prop1
paired like homeodomain factor 1 MGI:109330 |
Darker colors indicate more annotations |
Human Phenotypes | Hypoglycemic seizures |
Decreased response to growth hormone stimulation test |
Ectopic posterior pituitary |
Posterior pituitary hypoplasia |
Anterior pituitary agenesis |
Anterior pituitary hypoplasia |
Ectopic anterior pituitary gland |
Hypopituitarism |
Anterior hypopituitarism |
Abnormal prolactin level |
Reduced circulating prolactin concentration |
Gonadotropin deficiency |
Panhypopituitarism |
Pituitary hypothyroidism |
Optic nerve hypoplasia |
Septo-optic dysplasia |
Agenesis of corpus callosum |
Absent septum pellucidum |
Holoprosencephaly |
Intellectual disability |
Severe global developmental delay |
Seizure |
Disease(s) Associated with PROP1 | ||||||||||||||||||||||
hypopituitarism | ||||||||||||||||||||||
panhypopituitarism |
Mouse Phenotypes | abnormal pituitary gland morphology |
abnormal adenohypophysis development |
absent somatotrophs |
decreased thyrotroph cell number |
small adenohypophysis |
adenohypophysis hypoplasia |
abnormal neurohypophysis morphology |
abnormal pituitary gland development |
pituitary gland hypoplasia |
hypopituitarism |
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Availability | Mouse Genotype | ||||||||||
Prop1df/Prop1df | |||||||||||
Prop1tm1Rsd/Prop1tm1Rsd | |||||||||||
Prop1tm1Sac/Prop1tm1Sac | |||||||||||
Prop1tm1Sac/Prop1+ |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/03/2024 MGI 6.24 |
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