Symbol Name ID |
Wdfy3
WD repeat and FYVE domain containing 3 MGI:1096875 |
Darker colors indicate more annotations |
Human Phenotypes | Microcephaly |
Intellectual disability |
Disease(s) Associated with WDFY3 | ||
primary autosomal dominant microcephaly 18 |
Mouse Phenotypes | increased radial glial cell number |
premature neuronal precursor differentiation |
abnormal neuronal migration |
abnormal neuronal precursor proliferation |
abnormal forebrain development |
abnormal cortical intermediate zone morphology |
abnormal cortical ventricular zone morphology |
absent subplate |
increased forebrain size |
enlarged lateral ventricles |
enlarged third ventricle |
abnormal cerebral hemisphere morphology |
abnormal cerebral cortex morphology |
abnormal neocortex morphology |
increased neocortex size |
abnormal somatosensory cortex morphology |
abnormal stratification in cerebral cortex |
thin cerebral cortex |
small olfactory bulb |
abnormal embryonic/fetal subventricular zone morphology |
abnormal lateral ganglionic eminence morphology |
abnormal medial ganglionic eminence morphology |
decreased neuronal precursor cell number |
ectopic cortical neuron |
|
Availability | Mouse Genotype | ||||||||||||||||||||||||
Wdfy3disc/Wdfy3disc | |||||||||||||||||||||||||
Wdfy3tm1a(KOMP)Mbp/Wdfy3tm1a(KOMP)Mbp | |||||||||||||||||||||||||
Wdfy3tm1a(KOMP)Mbp/Wdfy3+ |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 08/02/2024 MGI 6.24 |
|
|