Symbol Name ID |
Crebbp
CREB binding protein MGI:1098280 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Microcephaly |
Agenesis of corpus callosum |
Hyperintensity of cerebral white matter on MRI |
Spina bifida |
Spina bifida occulta |
Incoordination |
Poor coordination |
EEG abnormality |
Delayed speech and language development |
Irritability |
Anxiety |
Autistic behavior |
Autism |
Hyperactivity |
Attention deficit hyperactivity disorder |
Impulsivity |
Self-mutilation |
Phonophobia |
Short attention span |
Intellectual disability |
Intellectual disability, mild |
Sleep abnormality |
Obstructive sleep apnea |
Hyperreflexia |
Unsteady gait |
Global developmental delay |
Delayed gross motor development |
Seizure |
Disease(s) Associated with CREBBP | ||||||||||||||||||||||||||||
Rubinstein-Taybi syndrome |
Mouse Phenotypes | nervous system phenotype |
seizures |
intracranial hemorrhage |
abnormal neural tube morphology |
incomplete rostral neuropore closure |
open neural tube |
abnormal nervous system morphology |
abnormal forebrain morphology |
exencephaly |
abnormal spinal cord morphology |
reduced long-term potentiation |
increased post-tetanic potentiation |
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Availability | Mouse Genotype | ||||||||||||
CrebbpGt(U-San)112Imeg/CrebbpGt(U-San)112Imeg | |||||||||||||
Crebbptm1Dli/Crebbptm1Dli | |||||||||||||
Crebbptm1Sis/Crebbptm1Sis | |||||||||||||
Crebbptm2Pkb/Crebbptm2Pkb | |||||||||||||
CrebbpGt(U-San)112Imeg/Crebbp+ | * | ||||||||||||
Crebbptm1.1Ltz/Crebbp+ | |||||||||||||
Tg(Camk2a-Crebbp*)1364Tabe/0 | |||||||||||||
Crebbptm1.2Ltz/Crebbptm1.2Ltz Tg(Camk2a-cre)T29-1Stl/0 (conditional) |
* |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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