Symbol
Name
ID

Slc32a1
solute carrier family 32 (GABA vesicular transporter), member 1
MGI:1194488

Phenotype annotations related to nervous system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes

Cortical dysplasia

Generalized cerebral atrophy/hypoplasia

Ataxia

Incoordination

Poor fine motor coordination

Bradykinesia

Tremor

EEG with spike-wave complexes

Anxiety

Autistic behavior

Obsessive-compulsive trait

Cognitive impairment

Developmental regression

Bilateral tonic-clonic seizure

Focal impaired awareness seizure

Generalized non-motor (absence) seizure

Focal-onset seizure

Generalized-onset seizure

Generalized myoclonic seizure

Febrile seizure (within the age range of 3 months to 6 years)

Atonic seizure

Status epilepticus

Atypical absence status epilepticus

Disease(s) Associated with SLC32A1

generalized epilepsy with febrile seizures plus

Mouse Phenotypes		nervous system phenotype	increased kindling response	tonic-clonic seizures	abnormal nervous system electrophysiology	abnormal nerve fiber response	abnormal inhibitory postsynaptic currents	abnormal inhibitory postsynaptic potential	decreased neurotransmitter release
Availability	Mouse Genotype	nervous system phenotype	increased kindling response	tonic-clonic seizures	abnormal nervous system electrophysiology	abnormal nerve fiber response	abnormal inhibitory postsynaptic currents	abnormal inhibitory postsynaptic potential	decreased neurotransmitter release
	Slc32a1^tm1Bros/Slc32a1^tm1Bros
	Slc32a1^tm1Yyan/Slc32a1^tm1Yyan
	Slc32a1^tm2(cre)Lowl/Slc32a1^tm2(cre)Lowl
	Agrp^tm1(cre)Lowl/Agrp⁺ Slc32a1^tm1Lowl/Slc32a1^tm1Lowl (conditional)
	Agrp^tm1(cre)Lowl/Agrp⁺ Slc32a1^tm1Lowl/Slc32a1^tm1Lowl Tg(Pomc1-hrGFP)1Lowl/0 (conditional)	*

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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