Symbol Name ID |
Apaf1
apoptotic peptidase activating factor 1 MGI:1306796 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Mouse Phenotypes | nervous system phenotype |
intracerebral hemorrhage |
decreased neuron apoptosis |
increased neuron apoptosis |
abnormal neuron differentiation |
abnormal neuronal migration |
abnormal neural tube morphology |
abnormal embryonic neuroepithelium morphology |
abnormal embryonic neuroepithelial layer differentiation |
increased embryonic neuroepithelium thickness |
delayed neural tube closure |
open neural tube |
spina bifida |
spina bifida occulta |
abnormal brain morphology |
abnormal brain development |
abnormal forebrain development |
abnormal cortical marginal zone morphology |
abnormal folding of telencephalic vesicles |
small embryonic telencephalon |
abnormal cranial flexure morphology |
hydrocephaly |
midbrain hyperplasia |
abnormal brain ventricle morphology |
abnormal fourth ventricle morphology |
abnormal lateral ventricle morphology |
choroid plexus hyperplasia |
abnormal third ventricle morphology |
abnormal forebrain morphology |
abnormal hypothalamus morphology |
hypothalamus hyperplasia |
abnormal thalamus morphology |
thalamus hyperplasia |
diencephalon hyperplasia |
abnormal telencephalon morphology |
abnormal cerebral hemisphere morphology |
thickened cerebral cortex |
abnormal hindbrain morphology |
abnormal embryonic/fetal subventricular zone morphology |
exencephaly |
abnormal neuron morphology |
motor neuron degeneration |
encephalomeningocele |
abnormal neuron physiology |
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Availability | Mouse Genotype | ||||||||||||||||||||||||||||||||||||||||||||
Apaf1fog/Apaf1fog | * | ||||||||||||||||||||||||||||||||||||||||||||
Apaf1Gt(IRESBetageo)XIX18Pgr/Apaf1Gt(IRESBetageo)XIX18Pgr | * | ||||||||||||||||||||||||||||||||||||||||||||
Apaf1tm1Her/Apaf1tm1Her | |||||||||||||||||||||||||||||||||||||||||||||
Apaf1tm1Mak/Apaf1tm1Mak | * | ||||||||||||||||||||||||||||||||||||||||||||
Apaf1ytj/Apaf1ytj | * | ||||||||||||||||||||||||||||||||||||||||||||
Apaf1fog/Apaf1Gt(IRESBetageo)XIX18Pgr | |||||||||||||||||||||||||||||||||||||||||||||
Apaf1fog/Apaf1tm1Her | |||||||||||||||||||||||||||||||||||||||||||||
Apaf1fog/Apaf1tm1Mak | |||||||||||||||||||||||||||||||||||||||||||||
Apaf1fog/Apaf1ytj |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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