Symbol Name ID |
Ndrg1
N-myc downstream regulated gene 1 MGI:1341799 |
Darker colors indicate more annotations |
Human Phenotypes | Abnormality of visual evoked potentials |
Frequent falls |
Onion bulb formation |
Segmental peripheral demyelination/remyelination |
Demyelinating peripheral neuropathy |
Axonal loss |
Postural tremor |
Abnormal auditory evoked potentials |
Decreased motor nerve conduction velocity |
Decreased nerve conduction velocity |
Decreased amplitude of sensory action potentials |
Areflexia |
Hyporeflexia |
Gait disturbance |
Inability to walk |
Unsteady gait |
Motor delay |
Somatic sensory dysfunction |
Impaired distal tactile sensation |
Distal sensory impairment |
Impaired distal proprioception |
Impaired distal vibration sensation |
Disease(s) Associated with NDRG1 | ||||||||||||||||||||||
Charcot-Marie-Tooth disease type 4D |
Mouse Phenotypes | abnormal axon morphology |
decreased myelin sheath thickness |
abnormal sciatic nerve morphology |
peripheral nervous system degeneration |
demyelination |
abnormal action potential |
decreased nerve conduction velocity |
decreased prepulse inhibition |
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Availability | Mouse Genotype | ||||||||
Ndrg1em1Lxli/Ndrg1em1Lxli | |||||||||
Ndrg1str/Ndrg1str | |||||||||
Ndrg1tm1Myta/Ndrg1tm1Myta | |||||||||
Ndrg1tm2b(KOMP)Wtsi/Ndrg1tm2b(KOMP)Wtsi |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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