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Symbol
Name
ID
Mapk1
mitogen-activated protein kinase 1
MGI:1346858
Phenotype annotations related to nervous system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Microcephaly
Cavum septum pellucidum
Delayed speech and language development
Anxiety
Aggressive behavior
Attention deficit hyperactivity disorder
Head-banging
Intellectual disability
Global developmental delay
Generalized-onset seizure
Infantile spasms
Disease(s) Associated with MAPK1
Noonan syndrome 13

Mouse Phenotypes
nervous system phenotype
abnormal neuron differentiation
abnormal cerebral cortex morphology
thin cerebral cortex
astrocytosis
Availability Mouse Genotype
Mapk1tm1Kuta/Mapk1tm1Kuta *
Mapk1tm1.2Kuta/Mapk1tm1.2Kuta
Tg(Nes-cre)1Kag/0  (conditional)
Mapk1tm1Gela/Mapk1tm1Gela
Tg(GFAP-cre)25Mes/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
08/02/2024
MGI 6.24
The Jackson Laboratory